According to specific product requirements (viscosity, temperature, oxygen sensitivity, aseptic issues etc.), Bram-Cor integrates his formulation plants with state-of-the-art: TRANSFER PANELS – to transfer process fluids through multiple process lines TRIBLENDERS – for air-free homogeneous mixing of liquids and solids SOLUTION TRANSFER CIRCUITS – through sanitary pipelines, pumps, fittings LAMINAR FLOW CABINETS – ensuring aseptic […]
Category: Pharmaceutical Processing
Purified Water (PW) & Water for Injection (WFI) – Reverse Osmosis Systems
Entirely Made in Italy, CROS sanitary Reverse Osmosis Systems are designed to produce compendial Purified Water (PW) and “cold” Water for Injection (WFI) through several water treatment steps, including Ultrafiltration (UF), according to feed water quality and production needs. Bram-Cor Water Treatment Equipment for pharmaceutical lines and plants is a wide range of cGMP systems, […]
Processing – Mixing Tanks and Formulation Vessels
Bram-Cor offers a complete range of preparation lines suitable for any pharmaceutical formulation: BIOREACTORS (reactor vessels, pressure vessels), MIXING TANKS (pressure tanks, mobile mixing vessels), CUSTOMIZED FORMULATION TANKS (for high purity water mixing with powders), ATMOSPHERIC TRANSFER TANKS. The accurate finishing and the high quality of the materials used in the construction of all our equipment ensure aseptic drug […]
Pharmaceutical Loop and User points
Bram-Cor integrates its PW-WFI-PS Generation equipment with state-of-the-art distribution loops. The Loop design is the result of a careful evaluation of Points of Use delivery criteria such as: Maximum istantaneous flow rate Pressure & temperature requirements Sanitization issues Periodic consumption requirements and duration Method of delivery […]
Water for Injection – Vapor compression Distillation systems
SAFE PRODUCTION OF WATER FOR INJECTION ACCORDING TO GMP AND FDA RULES Water for Injection (WFI) can be produced through distillation or, also, through a downstream unit of ultrafiltration in a Reverse Osmosis system. The more safe methods are the distillation processes, such as vapor compression distillation or multiple effect distillation. Therefore, Vapor compression distillation […]
