PURE STEAM. FROM STERILIZATION TO DIRECT CONTACT WITH A.P.I. BRAM-COR CPSG Pure Steam Generator produces dry, saturated steam, suitable for sterilization of pharmaceutical production plants, for direct contact with Active Pharmaceutical Ingredients, for Parenteral and Non-Parenteral dosage form applications. The steam, when condensed, meets USP requirements for Water-for-Injection. The steam is purified using centrifugal and gravity separation methods. […]
Category: Water Treatment Systems
Purified Water (PW) & Water for Injection (WFI) – Reverse Osmosis Systems
Entirely Made in Italy, CROS sanitary Reverse Osmosis Systems are designed to produce compendial Purified Water (PW) and “cold” Water for Injection (WFI) through several water treatment steps, including Ultrafiltration (UF), according to feed water quality and production needs. Bram-Cor Water Treatment Equipment for pharmaceutical lines and plants is a wide range of cGMP systems, […]
Pharmaceutical Loop and User points
Bram-Cor integrates its PW-WFI-PS Generation equipment with state-of-the-art distribution loops. The Loop design is the result of a careful evaluation of Points of Use delivery criteria such as: Maximum istantaneous flow rate Pressure & temperature requirements Sanitization issues Periodic consumption requirements and duration Method of delivery […]
Site Installation – Pickling and Passivation
Pickling and passivation processes, during the installation of a Bram-Cor Water Treatment System. Bram-Cor Water Treatment Equipment for pharmaceutical production lines: a full understanding of the drug production process is the key concept for correct design. Bram-Cor engineering focuses on fluid drugs sterile production processes, such a parenteral solutions, oral solutions, ophtalmic solutions. Bram-Cor work consists […]
Water for Injection – Vapor compression Distillation systems
SAFE PRODUCTION OF WATER FOR INJECTION ACCORDING TO GMP AND FDA RULES Water for Injection (WFI) can be produced through distillation or, also, through a downstream unit of ultrafiltration in a Reverse Osmosis system. The more safe methods are the distillation processes, such as vapor compression distillation or multiple effect distillation. Therefore, Vapor compression distillation […]
Water for Injection – Multiple Effect Distillation systems
Every Bram-Cor SMPT – Multiple Effect Distiller is designed and manufactured according to cGMP and produced compendial Water for Injection. Each unit contains a number of boiling columns (or effects, stills) with the first column producing pure steam, which is condensed and re-distilled in the following columns decreasing the operational costs. Heating for evaporation and cooling for condensation processes are […]
