Bram-Cor provides complete design, engineering, construction, installation and start-up of new pharmaceutical facilities, even assisting the Clients through scouting activities of potential Know How Licensor, transferring the Know How, providing Validation Master Plans and Standard Operating Procedures, validating, aligning industrial processes to URS and regulatory requirements. We propose reliable turnkey know-how, engineering and services about: LVP (Large Volume Parenterals) in […]
Author: Bram-Cor Archive - Italy
PS Production – Pure Steam Generator
PURE STEAM. FROM STERILIZATION TO DIRECT CONTACT WITH A.P.I. BRAM-COR CPSG Pure Steam Generator produces dry, saturated steam, suitable for sterilization of pharmaceutical production plants, for direct contact with Active Pharmaceutical Ingredients, for Parenteral and Non-Parenteral dosage form applications. The steam, when condensed, meets USP requirements for Water-for-Injection. The steam is purified using centrifugal and gravity separation methods. […]
Pharmaceutical Engineering – 3D Design
This album presents some 3D design from Bram-Cor Project and Engineering team. Every process follows rigorous cGMP-compliant Standard Operative Procedures. Specification, construction, and verification steps within the lifecycle are carried out according to GAMP “V-model”. Click here to see other Bram-Cor pharmaceutical lines (water treatment, processing, filling and packaging systems). © Bram-Cor SpA 2024
Processing – Ancillary Systems for Formulation and Preparation
According to specific product requirements (viscosity, temperature, oxygen sensitivity, aseptic issues etc.), Bram-Cor integrates his formulation plants with state-of-the-art: TRANSFER PANELS – to transfer process fluids through multiple process lines TRIBLENDERS – for air-free homogeneous mixing of liquids and solids SOLUTION TRANSFER CIRCUITS – through sanitary pipelines, pumps, fittings LAMINAR FLOW CABINETS – ensuring aseptic […]
Purified Water (PW) & Water for Injection (WFI) – Reverse Osmosis Systems
Entirely Made in Italy, CROS sanitary Reverse Osmosis Systems are designed to produce compendial Purified Water (PW) and “cold” Water for Injection (WFI) through several water treatment steps, including Ultrafiltration (UF), according to feed water quality and production needs. Bram-Cor Water Treatment Equipment for pharmaceutical lines and plants is a wide range of cGMP systems, […]
Pharmaceutical Conveyors and Turntables
These customized belt conveyors are designed to satisfy any requirement in the handling of pharmaceutical containers throughout the drug packaging process. Feedlines and output lines to and from production equipments can be specifically dimensioned for different container tipologies, such as glass bottles, PP bottles, small and large volume Bags. Click here to see other Bram-Cor pharmaceutical […]
Processing – Mixing Tanks and Formulation Vessels
Bram-Cor offers a complete range of preparation lines suitable for any pharmaceutical formulation: BIOREACTORS (reactor vessels, pressure vessels), MIXING TANKS (pressure tanks, mobile mixing vessels), CUSTOMIZED FORMULATION TANKS (for high purity water mixing with powders), ATMOSPHERIC TRANSFER TANKS. The accurate finishing and the high quality of the materials used in the construction of all our equipment ensure aseptic drug […]
Pharmaceutical Water Pretreatment Systems
CUSTOMIZABLE PROJECTS ON FEED WATER EVALUATION Each BRAM-COR PRTW Water Pretreatment System is customized upon a careful evaluation of feed water quality using local water analysis. Raw water can be pre-treated to remove contaminants (such as particulates, calcium and magnesium salts, heavy metals, organics and bacteria) through different steps, including: UV lamps and control […]
Pharmaceutical Loop and User points
Bram-Cor integrates its PW-WFI-PS Generation equipment with state-of-the-art distribution loops. The Loop design is the result of a careful evaluation of Points of Use delivery criteria such as: Maximum istantaneous flow rate Pressure & temperature requirements Sanitization issues Periodic consumption requirements and duration Method of delivery […]
Pharmaceutical Linear Filling for Bottles
The Bram-Cor FFIL pharmaceutical linear filling machine for bottles represents an evolution in the systems of filling for pharmaceutical rigid vessels, combining Maximum reliability, High precision in metering and Low maintenance costs. The process has been designed in order to offer the maximum functional easiness: The bottles are fed through a special sanitary belt A mechanical system provides […]
